Biomedical: Growing Companies

Columbus, Ohio

Cincinnati, Ohio

Milo Biotechnology is developing novel therapies based on follistatin, a protein that increases muscle mass and strength. Milo is targeting rare neuromuscular diseases, initiating a Phase I/II clinical trial in Becker muscular dystrophy and inclusion body myositis.

11000 Cedar Ave.
Cleveland, Ohio 44106

Phylogeny, Inc. accelerates the discovery of new drugs by enabling scientists to achieve excellence in functional genomic research. Phylogeny scientists have been instrumental in bringing important drugs in the areas of cancer, obesity and osteoporosis to clinical trial.

4100 Regent St., Suite M-2
Columbus, OH 43219

CardiOx Corp is a Central Ohio startup developing a noninvasive way to detect right-to-left heart shunts (often commonly referred to as "a hole in the heart. The CardiOx diagnostic system combines an injection of dye into a patient's heart with sensors on the ear to determine the presence of a shunt. The device also can be used to verify that surgery succeeded in patching the hole.

4100 Horizons Drive, Suite 100
Columbus, OH 43220

With a roster of patents ranging from medical diagnostics, stem-cell research and applied microbiology, NanoLogix has kept a low profile for much of its existence. No more.

843 N. Main St.
Hubbard, OH 44425

Vasostar, a part of the Frantz Medical Group, was formed in 2007 to develop technology invented in Israel that automates the “tapping” surgeons must do to remove life-threatening occlusions.

7740 Metric Drive
Mentor, OH 44060

Cincinnati's Mammotome now has a product to lessen discomfort and scarring in breast biopsies using a minimally invasive device known as a mammotome.

513-864-9000
300 E-Business Way, Fifth Floor
Cincinnati, OH 45241

Juventas Therapeutics is developing a groundbreaking line of regenerative therapies to treat life–threatening diseases.

216-445-0830
10265 Carnegie Ave.
Cleveland, OH 44106

Friends and business partners Jennifer Wexler and Kelly Bucci have poured their money, talent and time into a software company that helps hospitals catch billing errors that lead to lost dollars.

888-220-2769
241 Federal Plaza West
Youngstown, OH 44503

Checkpoint Surgical, of Cleveland, has introduced a tool to help doctors choose what tissue to cut during surgery, and more importantly, what not to cut.

877-478-9106
22901 Millcreek Blvd., Suite 110
Cleveland, OH 44122

OrthoHelix Surgical Designs, founded in 2004, develops orthopedic implants for hand and foot surgery - small bone areas.

866-904-3549
1065 Medina Rd, Ste 500
Medina, OH 44256

Touch Bionics' mechanical wizardry, some of which seemed the stuff of sci-fi not long ago, is helping thousands of people affected by medical conditions, industrial and agricultural accidents -- even war veterans.

614-388-8086
3455 Mill Run Drive, Suite 310-B
Hilliard, OH 43026

A pacemaker for the heart is commonplace. Now, Synapse Biomedical in Oberlin has developed one for the diaphragm.

440-774-2488
300 Artino St.
Oberlin, OH 44074

Algisys specializes in cost-effective growth and harvesting of algae for the production of nutritional oils and high protein biomass.

440-749-0510
6610 Hidden Woods Trail
Cleveland, 44143

Youngstown-based Syncro is changing the way critically ill patients are cared for — and tossing out the notion of a painfully difficult startup process.

234-855-1605
20 W. Federal St.
Youngstown, OH 44503

Dublin-based Neoprobe specializes in the development of diagnostic systems for cancer patients, making gamma detection treatments in tracking cancer more effective.

800-793-0079
425 Metro Place North, Suite 300
Dublin, OH 43017

The Cleveland HeartLab is taking its life-saving technology to heart. The company has developed a profile of tests focused on managing and reducing inflammation, a root cause of heart disease.

216-444-9886
10265 Carnegie Ave.
Cleveland, OH 44106

AxioMed Spine Corporation is advancing a next generation spinal disk replacement aimed at providing greater relief for hundreds of thousands suffering from degenerative spine disease.

216-587-5566
5350 Transportation Blvd., Suite 18
Garfield Heights, OH 44125

Neuros Medical is developing technology seeking to ease a variety of chronic aches from migraines to post surgical pain.

440-951-2565
4230 Route 306, Suite 305
Willoughby, OH 44094

In no other field is it as important to be perfect than the operating room. Simbionix helps doctors get all the practice they need.

216-229-2040
7100 Euclid Ave., Suite 180
Cleveland, OH 44103

With its new FDA approval in-hand, Beachwood-based NDI Medical is taking its newest product to market.

216-378-9106
22901 Millcreek Blvd., Suite 110
Cleveland, OH 44122

A million times each year in the U.S. a pregnant woman who is not remotely ready for delivery thinks she's entering preterm labor. Chagrin Falls-based CerviLenz wants her to know for sure -- at less cost.

440-337-4250
100 N. Main St., Suite 300
Chagrin Falls, OH 44022

877-828-1777
14656 Neo Parkway
Cleveland, OH 44128

Founded in 2008 by Dr. Stephen R. Branam, a local dentist with a big idea and 30 years of experience, Branam Oral Health Technologies, of Oregon, Ohio, is poised for a national market.

877-327-2626
3140 Dustin Road
Oregon, OH 43616

The medical device industry is one of the fastest-growing in the U.S. PediaWorks focuses on an area that is often ignored: medical devices for the littlest patients.

216-223-8877
11000 Cedar Ave. Suite 100
Cleveland, OH 44106

You've seen it in countless movies-- the soldier carrying his injured comrade off the battle field over his shoulder. Turns out that is exactly the wrong thing to do.

937-212-9020
2139 Dunshire Ct.
Miamisburg, OH 45342

No cure should aggravate a patient's health; yet during traditional radiation therapy for cancer patients, internal organs affected by cancer can shift, accidentally directing radiation to healthy tissue.

440-703-3210
2 Thermo Fisher Way
Oakwood Village, OH 44146

It can take as long as 24 hours to detect toxins in the body, meaning the people affected could be long gone by the time medical personnel figure it out. Thanks to the work of Crystal Diagnostics and its partners that may all change.

330-325-2511
4209 State Route 44
Rootstown, OH 44272

Potential migraine treatments range from pain medications and Botox injections to full-blown surgery. As founder of the American Migraine Center, Bahman Guyuron should know.

877-646-1222
29001 Cedar Road, Suite 326
Cleveland, OH 44124

On Front Street in East Toledo, sandwiched between two abandoned buildings, LexaMed -- a medical and pharmaceutical company -- opened for business with eight employees in 2006. It hasn't looked back.

888-232-5227
705 Front Street
Toledo, OH 43605

Besse Medical Supply in West Chester has accomplished what many small, family-run startups dream of: becoming part of a Fortune 26 company while holding onto family tradition.

800-543-2111
9075 Centre Pointe Drive, Suite 140
West Chester, OH 45069

Meridian makes, markets and distributes a broad range of diagnostic test kits, purified reagents and related products and technologies for a variety of biomedical customers in more than 60 countries.

513-271-3700
3471 River Hills Drive
Cincinnati, OH 45244

As a urological surgeon for OhioHealth, Wayne Poll knew there must be a way to keep his laparoscopic lenses clear without constantly having to stop and clean them. While it took him 10 years to bring that vision to fruition, Poll's FloShield is now in the marketplace.

614-484-5036
1275 Kinnear Road
Columbus, OH 43212

CardioInsight Technologies is working to develop the first non-invasive, real-time, beat-to-beat simultaneous mapping solution for treatment of cardiac arrhythmias and heart failure.

216-453-5950
11000 Cedar Ave., Suite 210
Cleveland, OH 44106

Akebia Therapeutics is banking on two revolutionary drugs for treatment of anemia, blood vessel leakage and cancer.

513-618-0931
10151 Carver Road, Suite 205
Cincinnati, OH 45242

Athersys is a clinical-stage biopharmaceutical company with a growing pipeline of "potential best-in-class therapeutics" it hopes will provide some answers to issues such as heart attacks, obesity and cognitive disorders

216-431-9900
3201 Carnegie Ave.
Cleveland, OH 44115

If it comes time for a biopsy, would you rather make two stops -- first, to your family doc, then to the dermatologist -- or one? The folks at CleveX believe that patients will prefer the latter.

877-253-8911
1275 Kinnear Road
Columbus, OH 43212

AssureRx, LLC, based in Cincinnati, is developing the next generation of personalized medicines, including a lab-developed test that will measure and analyze genetic variants in psychiatric medicine.

513-234-0510
7264 Columbia Road, Suite 600
Maineville, OH 45039

Akron-based FMI Technologies is working on a new tool that can peel images of the brain back to the molecular level – where the cell-killing processes of Alzheimer's disease percolate.

330-253-0200
26 S. Main St., Suite 812
Akron, OH 44311

After working with a patient in 1999 whose blood pressure was unstable as plasma seeped out of her blood vessels University of Toledo doctors sought t a treatment. ADS Biotechnology was born.